Association of Insulin Resistance and Inflammation With Peripheral Arterial Disease | Zendy

Reena L. Pande | Zendy; Todd S. Perlstein | Zendy; Joshua A. Beckman | Zendy; Mark A. Creager | Zendy

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Association of Insulin Resistance and Inflammation With Peripheral Arterial Disease

Author(s) -

Reena L. Pande,

Todd S. Perlstein,

Joshua A. Beckman,

Mark A. Creager

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.721878

Subject(s) - medicine , insulin resistance , quartile , national health and nutrition examination survey , body mass index , odds ratio , c reactive protein , gastroenterology , endocrinology , insulin , inflammation , confidence interval , population , environmental health

Although the role of inflammation in the pathophysiology of peripheral arterial disease (PAD) is well established, the contribution of insulin resistance (IR) to PAD is less clear. We hypothesized that IR is associated with PAD and that the presence of IR would influence the association between C-reactive protein (CRP) and PAD, an association established predominantly in healthy individuals.

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