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PD-L1 and PD-L2 are ligands for the inhibitory receptor programmed death-1 (PD-1), which is an important regulator of immune responses. PD-L1 is induced on cardiac endothelial cells under inflammatory conditions, but little is known about its role in regulating immune injury in the heart.

Endothelial Programmed Death-1 Ligand 1 (PD-L1) Regulates CD8+T-Cell–Mediated Injury in the Heart

Endothelial Programmed Death-1 Ligand 1 (PD-L1) Regulates CD8⁺T-Cell–Mediated Injury in the Heart