Osteoprotegerin Inhibits Vascular Calcification Without Affecting Atherosclerosis in  ldlr (−/−)  Mice | Zendy

Sean Morony | Zendy; Yin Tintut | Zendy; Zina Zhang | Zendy; Russell C. Cattley | Zendy; Gwyneth Van | Zendy; Denise Dwyer | Zendy; Marina Stolina | Zendy; Paul J. Kostenuik | Zendy; Linda L. Demer | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Osteoprotegerin Inhibits Vascular Calcification Without Affecting Atherosclerosis in ldlr ^(−/−) Mice

Author(s) -

Sean Morony,

Yin Tintut,

Zina Zhang,

Russell C. Cattley,

Gwyneth Van,

Denise Dwyer,

Marina Stolina,

Paul J. Kostenuik,

Linda L. Demer

Publication year - 2008

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.707380

Subject(s) - osteoprotegerin , medicine , calcification , osteocalcin , endocrinology , lesion , arteriosclerosis , pathology , receptor , alkaline phosphatase , biology , biochemistry , activator (genetics) , enzyme

The role of osteoprotegerin in vascular disease is unclear. Recent observational studies show that serum osteoprotegerin levels are associated with the severity and progression of coronary artery disease, atherosclerosis, and vascular calcification in patients. However, genetic and treatment studies in mice suggest that osteoprotegerin may protect against vascular calcification.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research