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Apolipoprotein A-II Is Inversely Associated With Risk of Future Coronary Artery Disease
Author(s) -
Rakesh S. Birjmohun,
Geesje M. DallingaThie,
Jan Albert Kuivenhoven,
Erik S.G. Stroes,
James D. Otvos,
Nicholas J. Wareham,
Robert Luben,
John J.P. Kastelein,
KayTee Khaw,
S. Matthijs Boekholdt
Publication year - 2007
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.107.704031
Subject(s) - medicine , coronary artery disease , cardiology , apolipoprotein b , disease , atherosclerotic cardiovascular disease , risk factor , cholesterol
Although the vasculoprotective effects of apolipoprotein A-I (apoA-I), the major protein associated with high-density lipoprotein, have been universally accepted, apoA-II has been suggested to have poor antiatherogenic or even proatherogenic properties. To study this suggestion more closely, we evaluated how serum levels of apoA-II and apoA-I relate to the risk of future coronary artery disease (CAD) in a large, prospective study.

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