Ventricular Preexcitation Modulates Strain and Attenuates Cardiac Remodeling in a Swine Model of Myocardial Infarction
Author(s) -
Allan Shuros,
Rodney W. Salo,
Viorel G. Florea,
Joseph Pastore,
Michael A. Kuskowski,
Y. Chandrashekhar,
Inder S. Anand
Publication year - 2007
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.107.696294
Subject(s) - medicine , cardiology , myocardial infarction , ventricular remodeling , infarction , sonomicrometry , hemodynamics
Myocardial infarction modifies the distribution of stress within the heart, increasing wall stress in ischemic and surrounding tissue, which often leads to adverse left ventricular remodeling. Electrical preexcitation pacing with appropriate timing of high-stress regions can reduce local strain and may attenuate global remodeling.
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