Brachial Artery Flow-Mediated Dilation and Asymmetrical Dimethylarginine in the Cardiovascular Risk in Young Finns Study
Author(s) -
Markus Juonala,
Jorma Viikari,
Georg Alfthan,
Jukka Marniemi,
Mika Kähönen,
Leena Taittonen,
Tomi Laitinen,
Olli T. Raitakari
Publication year - 2007
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.107.690016
Subject(s) - brachial artery , medicine , cardiology , asymmetric dimethylarginine , risk factor , population , endothelium , univariate analysis , endothelial dysfunction , renal function , endocrinology , blood pressure , arginine , multivariate analysis , biochemistry , chemistry , environmental health , amino acid
Elevated asymmetrical dimethylarginine (ADMA) is a novel risk factor for atherosclerosis that may impair endothelial function by interfering with endothelial nitric oxide synthesis. To gain insight into the effects of ADMA on systemic endothelial function, we examined the association between ADMA and brachial artery flow-mediated dilation (FMD) in a large population of young adults.
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