Family History of Premature Coronary Heart Disease and Coronary Artery Calcification | Zendy

Khurram Nasir | Zendy; Matthew J. Budoff | Zendy; Nathan D. Wong | Zendy; Maren T. Scheuner | Zendy; David M. Herrington | Zendy; Donna K. Arnett | Zendy; Moysés Szklo | Zendy; Philip Greenland | Zendy; Roger S. Blumenthal | Zendy

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Family History of Premature Coronary Heart Disease and Coronary Artery Calcification

Author(s) -

Khurram Nasir,

Matthew J. Budoff,

Nathan D. Wong,

Maren T. Scheuner,

David M. Herrington,

Donna K. Arnett,

Moysés Szklo,

Philip Greenland,

Roger S. Blumenthal

Publication year - 2007

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.107.688739

Subject(s) - medicine , family history , asymptomatic , cohort , framingham risk score , framingham heart study , risk factor , cardiology , disease

A family history of premature coronary heart disease (CHD) is a known risk factor for CHD events. The purpose of this study was to assess the strength of the association between a family history of premature CHD and coronary artery calcification (CAC) in a multiethnic cohort of asymptomatic individuals. We also sought to determine whether individuals with a reported family history of premature CHD have an increased atherosclerotic burden among those classified as being at low to intermediate risk on the basis of the conventional Framingham risk score.

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