Shedding of the Endothelial Glycocalyx in Patients Undergoing Major Vascular Surgery With Global and Regional Ischemia | Zendy

Markus Rehm | Zendy; Dirk Bruegger | Zendy; F. Christ | Zendy; Peter Conzen | Zendy; Manfred Thiel | Zendy; Matthias Jacob | Zendy; Daniel Chappell | Zendy; Mechthild Stoeckelhuber | Zendy; Ulrich Welsch | Zendy; Bruno Reichart | Zendy; Klaus Peter | Zendy; Bernhard F. Becker | Zendy

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Shedding of the Endothelial Glycocalyx in Patients Undergoing Major Vascular Surgery With Global and Regional Ischemia

Author(s) -

Markus Rehm,

Dirk Bruegger,

F. Christ,

Peter Conzen,

Manfred Thiel,

Matthias Jacob,

Daniel Chappell,

Mechthild Stoeckelhuber,

Ulrich Welsch,

Bruno Reichart,

Klaus Peter,

Bernhard F. Becker

Publication year - 2007

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.684852

Subject(s) - glycocalyx , heparan sulfate , medicine , ischemia , cardiopulmonary bypass , syndecan 1 , endothelium , circulatory system , cardiology , pathology , anesthesia , immunology , heparin , biology , biochemistry , cell

The astonishing thickness of the endothelial glycocalyx, which rivals that of endothelial cells in the microvasculature, was disclosed in the last 15 years. As already demonstrated, this structure plays a key role in the regulation of inflammation and vascular permeability.

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