Molecular Imaging of Inflammation in Atherosclerosis With Targeted Ultrasound Detection of Vascular Cell Adhesion Molecule-1
Author(s) -
Beat A. Kaufmann,
John M. Sanders,
Christopher K. Davis,
Aris Xie,
Patrick Aldred,
Ian J. Sarembock,
Jonathan R. Lindner
Publication year - 2007
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.106.684738
Subject(s) - microbubbles , medicine , aorta , inflammation , molecular imaging , apolipoprotein b , ultrasound , cell adhesion molecule , vcam 1 , pulsatile flow , pathology , thoracic aorta , endothelial stem cell , icam 1 , immunology , radiology , in vivo , chemistry , biochemistry , in vitro , biology , cholesterol , microbiology and biotechnology
The ability to image vascular inflammatory responses may allow early diagnosis and treatment of atherosclerosis. We hypothesized that molecular imaging of vascular cell adhesion molecule-1 (VCAM-1) expression with contrast-enhanced ultrasound (CEU) could be used for this purpose.
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