Early Repair of Moderate Ischemic Mitral Regurgitation Reverses Left Ventricular Remodeling | Zendy

Rоnen Beeri | Zendy; Chaim Yosefy | Zendy; Jorge Guerrero | Zendy; Suzan Abedat | Zendy; Mark D. Handschumacher | Zendy; Robert E. Stroud | Zendy; Suzanne Sullivan | Zendy; Miguel Chaput | Zendy; Dan Gilon | Zendy; Gus J. Vlahakes | Zendy; Francis G. Spinale | Zendy; Roger J. Hajjar | Zendy; Robert A. Levine | Zendy

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Early Repair of Moderate Ischemic Mitral Regurgitation Reverses Left Ventricular Remodeling

Author(s) -

Rоnen Beeri,

Chaim Yosefy,

Jorge Guerrero,

Suzan Abedat,

Mark D. Handschumacher,

Robert E. Stroud,

Suzanne Sullivan,

Miguel Chaput,

Dan Gilon,

Gus J. Vlahakes,

Francis G. Spinale,

Roger J. Hajjar,

Robert A. Levine

Publication year - 2007

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.681114

Subject(s) - medicine , ventricular remodeling , cardiology , ventricle , mitral valve repair , preload , ejection fraction , contractility , end diastolic volume , mitral regurgitation , volume overload , infarction , myocardial infarction , stroke volume , heart failure , hemodynamics

Mitral regurgitation (MR) doubles postmyocardial infarction (MI) mortality. We have shown that moderate MR augments remodeling in an apical MI model (no intrinsic MR) with independent left ventricle-to-left atrial MR-type flow. We hypothesized that repairing moderate MR 1 month after MI reverses this remodeling.

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