The Cardiotomy Trial | Zendy

Fraser D. Rubens | Zendy; Munir Boodhwani | Zendy; Thierry Mesana | Zendy; Denise Wozny | Zendy; George Wells | Zendy; Howard J. Nathan | Zendy

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The Cardiotomy Trial

Author(s) -

Fraser D. Rubens,

Munir Boodhwani,

Thierry Mesana,

Denise Wozny,

George Wells,

Howard J. Nathan

Publication year - 2007

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.678987

Subject(s) - medicine , blood product , surgery , cardiopulmonary bypass , anesthesia , autotransfusion , cardiac surgery , blood transfusion , postoperative cognitive dysfunction , fresh frozen plasma , partial thromboplastin time , platelet , cognition , psychiatry

Reinfusion of unprocessed cardiotomy blood during cardiac surgery can introduce particulate material into the cardiopulmonary bypass circuit, which may contribute to postoperative cognitive dysfunction. On the other hand, processing of this blood by centrifugation and filtration removes coagulation factors and may potentially contribute to coagulopathy. We sought to evaluate the effects of cardiotomy blood processing on blood product use and neurocognitive functioning after cardiac surgery.

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