Adiponectin Cardioprotection After Myocardial Ischemia/Reperfusion Involves the Reduction of Oxidative/Nitrative Stress | Zendy

Ling Tao | Zendy; Erhe Gao | Zendy; Xiangying Jiao | Zendy; Yuexing Yuan | Zendy; Shuzhuang Li | Zendy; Theodore A. Christopher | Zendy; Bernard L. Lopez | Zendy; Walter Koch | Zendy; Lawrence Chan | Zendy; Barry J. Goldstein | Zendy; Xin L. | Zendy

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Adiponectin Cardioprotection After Myocardial Ischemia/Reperfusion Involves the Reduction of Oxidative/Nitrative Stress

Author(s) -

Ling Tao,

Erhe Gao,

Xiangying Jiao,

Yuexing Yuan,

Shuzhuang Li,

Theodore A. Christopher,

Bernard L. Lopez,

Walter Koch,

Lawrence Chan,

Barry J. Goldstein,

Xin L.

Publication year - 2007

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.666941

Subject(s) - peroxynitrite , adiponectin , nicotinamide adenine dinucleotide phosphate , medicine , endocrinology , superoxide , cardioprotection , oxidative stress , ischemia , reperfusion injury , nadph oxidase , nitric oxide , nitric oxide synthase , pharmacology , oxidase test , biochemistry , chemistry , diabetes mellitus , enzyme , insulin resistance

Several clinical studies have demonstrated that levels of adiponectin are significantly reduced in patients with type 2 diabetes and that adiponectin levels are inversely related to the risk of myocardial ischemia. The present study was designed to determine the mechanism by which adiponectin exerts its protective effects against myocardial ischemia/reperfusion.

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