Cardiac Tissue Engineering in an In Vivo Vascularized Chamber
Author(s) -
Andrew N. Morritt,
Susan Bortolotto,
Rodney J. Dilley,
Xiaolian Han,
Andrew R. Kompa,
David McCombe,
Christine E. Wright,
Silviu Itescu,
James A. Angus,
Wayne A. Morrison
Publication year - 2007
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.106.657379
Subject(s) - medicine , desmin , ventricle , in vivo , tissue engineering , extracellular matrix , myocyte , anatomy , immunostaining , cardiac muscle , cardiac ventricle , pathology , immunohistochemistry , biomedical engineering , microbiology and biotechnology , biology , vimentin
Cardiac tissue engineering offers the prospect of a novel treatment for acquired or congenital heart defects. We have created vascularized pieces of beating cardiac muscle in the rat that are as thick as the adult rat right ventricle wall.
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