Theoretical Impact of the Injection of Material Into the Myocardium | Zendy

Samuel Wall | Zendy; Joseph C. Walker | Zendy; Kevin E. Healy | Zendy; Mark B. Ratcliffe | Zendy; Julius M. Guccione | Zendy

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Theoretical Impact of the Injection of Material Into the Myocardium

Author(s) -

Samuel Wall,

Joseph C. Walker,

Kevin E. Healy,

Mark B. Ratcliffe,

Julius M. Guccione

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.657270

Subject(s) - ventricle , medicine , myocardial infarction , cardiology , stroke volume , ejection fraction , diastole , border zone , systole , cardiac function curve , heart failure , blood pressure

To treat cardiac injuries created by myocardial infarcts, current approaches seek to add cells and/or synthetic extracellular matrices to the damaged ventricle to restore function. Because definitive myocardial regeneration remains undemonstrated, we propose that cardiac changes observed from implanted materials may result from altered mechanisms of the ventricle.

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