Tumor Necrosis Factor-α Receptor p75 Is Required in Ischemia-Induced Neovascularization | Zendy

David A. Goukassian | Zendy; Gangjian Qin | Zendy; Christine Dolan | Zendy; Toshinori Murayama | Zendy; Marcy Silver | Zendy; Cynthia J. Curry | Zendy; Elizabeth Eaton | Zendy; Corinne Luedemann | Zendy; Hong Ma | Zendy; Takayuki Asahara | Zendy; Victor Zak | Zendy; Shanu Mehta | Zendy; Aaron Burg | Zendy; Tina Thorne | Zendy; Raj Kishore | Zendy; Douglas W. Losordo | Zendy

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Tumor Necrosis Factor-α Receptor p75 Is Required in Ischemia-Induced Neovascularization

Author(s) -

David A. Goukassian,

Gangjian Qin,

Christine Dolan,

Toshinori Murayama,

Marcy Silver,

Cynthia J. Curry,

Elizabeth Eaton,

Corinne Luedemann,

Hong Ma,

Takayuki Asahara,

Victor Zak,

Shanu Mehta,

Aaron Burg,

Tina Thorne,

Raj Kishore,

Douglas W. Losordo

Publication year - 2007

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.647255

Subject(s) - progenitor cell , medicine , angiogenesis , neovascularization , endothelial stem cell , endothelial progenitor cell , bone marrow , vascular endothelial growth factor , tumor necrosis factor alpha , stem cell , immunology , endocrinology , biology , microbiology and biotechnology , biochemistry , vegf receptors , in vitro

Aging is a risk factor for coronary and peripheral artery disease. Tumor necrosis factor-alpha (TNF-alpha), a proinflammatory cytokine, is expressed in ischemic tissue and is known to modulate angiogenesis. Little is known about the role of TNF-alpha receptors (TNFR1/p55 and TNFR2/p75) in angiogenic signaling.

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