Hypertrophic Cardiomyopathy Is Predominantly a Disease of Left Ventricular Outflow Tract Obstruction
Author(s) -
Martin S. Maron,
Iacopo Olivotto,
Andrey G. Zenovich,
Mark S. Link,
Natesa G. Pandian,
Jeffery T. Kuvin,
Stefano Nistri,
Franco Cecchi,
James E. Udelson,
Barry J. Maron
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.106.644682
Subject(s) - medicine , ventricular outflow tract obstruction , hypertrophic cardiomyopathy , cardiology , cardiomyopathy , outflow , ventricular outflow tract , heart disease , heart failure , physics , meteorology
Nonobstructive hypertrophic cardiomyopathy (HCM) has been regarded as the predominant hemodynamic form of the disease on the basis of assessment of outflow gradient under resting conditions. We sought to prospectively define the prevalence, clinical profile, and significance of left ventricular (LV) outflow tract obstruction under resting conditions and with physiological exercise in a large HCM cohort.
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