Accelerated Mitochondrial Adenosine Diphosphate/Adenosine Triphosphate Transport Improves Hypertension-Induced Heart Disease | Zendy

Thomas Walther | Zendy; Carsten Tschöpe | Zendy; Anja SternerKock | Zendy; Dirk Westermann | Zendy; Silvia HeringerWalther | Zendy; Alexander Riad | Zendy; A. Nikolic | Zendy; Yong Wang | Zendy; Linda Ebermann | Zendy; WolfEberhard Siems | Zendy; Michael Bäder | Zendy; Mehdi Shakibaei | Zendy; HeinzPeter Schultheiss | Zendy; Andrea Dörner | Zendy

Open Access

Accelerated Mitochondrial Adenosine Diphosphate/Adenosine Triphosphate Transport Improves Hypertension-Induced Heart Disease

Author(s) -

Thomas Walther,

Carsten Tschöpe,

Anja SternerKock,

Dirk Westermann,

Silvia HeringerWalther,

Alexander Riad,

A. Nikolic,

Yong Wang,

Linda Ebermann,

WolfEberhard Siems,

Michael Bäder,

Mehdi Shakibaei,

HeinzPeter Schultheiss,

Andrea Dörner

Publication year - 2007

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.643296

Subject(s) - medicine , adenosine triphosphate , adenosine , adenosine diphosphate , mitochondrion , cardiology , biochemistry , platelet , platelet aggregation , chemistry

Strong evidence suggests that mitochondrial malfunction, which leads to disturbed energy metabolism and stimulated apoptosis, is a linchpin in the induction and manifestation of cardiac failure. An adequate exchange of ATP and ADP over the inner mitochondrial membrane by the adenine nucleotide translocase (ANT) is thereby essential to guarantee the cellular energy supply.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research