Effect of Celecoxib on Cardiovascular Events and Blood Pressure in Two Trials for the Prevention of Colorectal Adenomas
Author(s) -
Scott D. Solomon,
Marc A. Pfeffer,
John J.V. McMurray,
Rob Fowler,
Peter Finn,
Bernard Levin,
Craig Eagle,
Ernest T. Hawk,
Mariajosé Lechuga,
Ann G. Zauber,
Monica M. Bertagnolli,
Nadir Arber,
Janet Wittes
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.106.636746
Subject(s) - medicine , celecoxib , hazard ratio , myocardial infarction , blood pressure , placebo , adenoma , stroke (engine) , colorectal adenoma , confidence interval , rofecoxib , colorectal cancer , surgery , gastroenterology , cancer , cyclooxygenase , pathology , mechanical engineering , biochemistry , chemistry , alternative medicine , engineering , enzyme
Cyclooxygenase-2 (COX-2) inhibitors have been shown to reduce colorectal adenomas but have been associated with increased cardiovascular risk.
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