Diurnal, Seasonal, and Blood-Processing Patterns in Levels of Circulating Fibrinogen, Fibrin D-Dimer, C-Reactive Protein, Tissue Plasminogen Activator, and von Willebrand Factor in a 45-Year-Old Population | Zendy

Alicja R. Rudnicka | Zendy; Ann Rumley | Zendy; Gordon Lowe | Zendy; David P. Strachan | Zendy

Open Access

Diurnal, Seasonal, and Blood-Processing Patterns in Levels of Circulating Fibrinogen, Fibrin D-Dimer, C-Reactive Protein, Tissue Plasminogen Activator, and von Willebrand Factor in a 45-Year-Old Population

Author(s) -

Alicja R. Rudnicka,

Ann Rumley,

Gordon Lowe,

David P. Strachan

Publication year - 2007

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.635169

Subject(s) - fibrinogen , von willebrand factor , d dimer , medicine , fibrin , plasminogen activator , diurnal temperature variation , tissue plasminogen activator , c reactive protein , endocrinology , population , fibrinolysis , immunology , platelet , inflammation , environmental health , atmospheric sciences , geology

Circulating levels of fibrinogen, fibrin D-dimer, C-reactive protein (CRP), tissue plasminogen activator antigen (t-PA) and von Willebrand factor are associated with incident coronary heart disease. We describe cross-sectional diurnal, seasonal, and blood-processing patterns for these variables, and assess whether they represent important sources of variability that should be taken into account in epidemiological studies or for additional risk prediction in individuals.

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