Atrioventricular Ring Reentry in Embryonic Mouse Hearts
Author(s) -
Miguel Valderrábano,
Fuhua Chen,
Amish S. Dave,
Scott T. Lamp,
Thomas S. Klitzner,
James N. Weiss
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.106.633727
Subject(s) - reentry , medicine , optical mapping , cardiology , electrical conduction system of the heart , stimulation , anatomy , electrocardiography
During development, AV conduction switches from base-to-apex to apex-to-base conduction after emergence of the conduction system. We hypothesize that after this transition, the bulk of the AV ring, although no longer required for AV conduction, remains transiently able to conduct, providing a potential arrhythmia substrate. We studied AV conduction during this transition and its sensitivity to autonomic modulation.
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