Impaired Chronotropic and Vasodilator Reserves Limit Exercise Capacity in Patients With Heart Failure and a Preserved Ejection Fraction | Zendy

Barry A. Borlaug | Zendy; Vojtěch Melenovský | Zendy; Stuart D. Russell | Zendy; Kristy Kessler | Zendy; Karel Pacák | Zendy; Lewis C. Becker | Zendy; David A. Kass | Zendy

Open Access

Impaired Chronotropic and Vasodilator Reserves Limit Exercise Capacity in Patients With Heart Failure and a Preserved Ejection Fraction

Author(s) -

Barry A. Borlaug,

Vojtěch Melenovský,

Stuart D. Russell,

Kristy Kessler,

Karel Pacák,

Lewis C. Becker,

David A. Kass

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.632745

Subject(s) - medicine , cardiology , heart failure , heart failure with preserved ejection fraction , stroke volume , ejection fraction , cardiac output , chronotropic , exercise intolerance , heart rate , diastole , hemodynamics , blood pressure

Nearly half of patients with heart failure have a preserved ejection fraction (HFpEF). Symptoms of exercise intolerance and dyspnea are most often attributed to diastolic dysfunction; however, impaired systolic and/or arterial vasodilator reserve under stress could also play an important role.

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