Randomized Trial of Atorvastatin for Reduction of Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Author(s) -
Giuseppe Patti,
Massimo Chello,
Dario Candura,
Vincenzo Pasceri,
Andrea D’Ambrosio,
Elvio Covino,
Germano Di Sciascio
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.106.621763
Subject(s) - medicine , atorvastatin , atrial fibrillation , odds ratio , placebo , randomized controlled trial , confidence interval , incidence (geometry) , clinical endpoint , cardiology , cardiac surgery , anesthesia , randomization , surgery , physics , alternative medicine , pathology , optics
Atrial fibrillation (AF) after cardiac surgery is associated with increased risk of complications, length of stay, and cost of care. Observational evidence suggests that patients who have undergone previous statin therapy have a lower incidence of postoperative AF. We tested this observation in a randomized, controlled trial.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom