Open AccessResponse to Letter Regarding Article “Atherosclerosis 2005: Recent Discoveries and Novel Hypotheses”
Author(s) -
Pascal J. GoldschmidtClermont,
Gregory K.W. Lam,
Victor J. Dzau,
Chunming Dong,
Joanne Kurtzberg,
Mark A. Creager,
Douglas W. Losordo,
Momtaz K. Wassef
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.106.617068
Subject(s) - medicine , library science , gerontology , family medicine , computer science
We thank Drs Williams and Tabas for their interest in our work1 and agree that there is a substantial body of evidence supporting the role of hyperlipidemia in atherogenesis. In our review, we addressed this point and indicated that cholesterol may be sufficient to alter the homeostasis of the arterial wall in susceptible individuals even at levels previously considered “normal.” To explain the spectrum of atherosclerotic lesions at any given lipid level, we hypothesized that some individuals might have robust …
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