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Estrogen Receptor α Polymorphism and Risk of Cardiovascular Disease, Cancer, and Hip Fracture
Author(s) -
Alisa D. Kjærgaard,
Christina Ellervik,
Anne TybjærgHansen,
C. K. Axelsson,
Marie-Louise M. Grønholdt,
Peer Grande,
Gorm Boje Jensen,
Børge G. Nordestgaard
Publication year - 2007
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.106.615567
Subject(s) - medicine , breast cancer , myocardial infarction , odds ratio , population , cardiology , stroke (engine) , endometrial cancer , hip fracture , cancer , gastroenterology , gynecology , oncology , osteoporosis , mechanical engineering , environmental health , engineering
We hypothesized that the estrogen receptor alpha (ESR1) IVS1-397T/C polymorphism affects high-density lipoprotein cholesterol response to hormone replacement therapy and risk of cardiovascular disease (CVD), cancer of reproductive organs, and hip fracture.

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