Localization of Na + Channel Isoforms at the Atrioventricular Junction and Atrioventricular Node in the Rat | Zendy

Shin Yoo | Zendy; Halina Dobrzynski | Zendy; Vadim V. Fedorov | Zendy; ShangZhong Xu | Zendy; Tomoko T. Yamanushi | Zendy; Sandra A. Jones | Zendy; Mitsuru Yamamoto | Zendy; V. Nikolski | Zendy; Igor R. Efimov | Zendy; Mark R. Boyett | Zendy

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Localization of Na ⁺ Channel Isoforms at the Atrioventricular Junction and Atrioventricular Node in the Rat

Author(s) -

Shin Yoo,

Halina Dobrzynski,

Vadim V. Fedorov,

ShangZhong Xu,

Tomoko T. Yamanushi,

Sandra A. Jones,

Mitsuru Yamamoto,

V. Nikolski,

Igor R. Efimov,

Mark R. Boyett

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.106.613182

Subject(s) - atrioventricular node , immunolabeling , medicine , bundle branches , bundle of his , anatomy , desmoplakin , electrical conduction system of the heart , gene isoform , immunohistochemistry , tachycardia , biology , cell , electrocardiography , biochemistry , gene

The electrical activity of the atrioventricular node (AVN) is functionally heterogeneous, but how this relates to distinct cell types and the 3-dimensional structure of the AVN is unknown. To address this, we have studied the expression of Na(V)1.5 and other Na+ channel isoforms in the AVN.

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