Evidence of a Dominant Backward-Propagating “Suction” Wave Responsible for Diastolic Coronary Filling in Humans, Attenuated in Left Ventricular Hypertrophy | Zendy

Justin E. Davies | Zendy; Zachary I. Whinnett | Zendy; Dárrel P. Francis | Zendy; Charlotte Manisty | Zendy; Jazmín AguadoSierra | Zendy; Keith Willson | Zendy; Rodney A. Foale | Zendy; Iqbal Malik | Zendy; Alun D. Hughes | Zendy; Kim H. Parker | Zendy; Jamil Mayet | Zendy

Open Access

Evidence of a Dominant Backward-Propagating “Suction” Wave Responsible for Diastolic Coronary Filling in Humans, Attenuated in Left Ventricular Hypertrophy

Author(s) -

Justin E. Davies,

Zachary I. Whinnett,

Dárrel P. Francis,

Charlotte Manisty,

Jazmín AguadoSierra,

Keith Willson,

Rodney A. Foale,

Iqbal Malik,

Alun D. Hughes,

Kim H. Parker,

Jamil Mayet

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.603050

Subject(s) - medicine , cardiology , left ventricular hypertrophy , blood flow , suction , diastole , artery , blood pressure , intensity (physics) , coronary circulation , hemodynamics , physics , quantum mechanics , meteorology

Coronary blood flow peaks in diastole when aortic blood pressure has fallen. Current models fail to completely explain this phenomenon. We present a new approach-using wave intensity analysis-to explain this phenomenon in normal subjects and to evaluate the effects of left ventricular hypertrophy (LVH).

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