Oxidized Lipid-Driven Chemokine Receptor Switch, CCR2 to CX3CR1, Mediates Adhesion of Human Macrophages to Coronary Artery Smooth Muscle Cells Through a Peroxisome Proliferator-Activated Receptor γ–Dependent Pathway | Zendy

Jana Barlic | Zendy; Yuan Zhang | Zendy; John F. Foley | Zendy; Philip M. Murphy | Zendy

Open Access

Oxidized Lipid-Driven Chemokine Receptor Switch, CCR2 to CX3CR1, Mediates Adhesion of Human Macrophages to Coronary Artery Smooth Muscle Cells Through a Peroxisome Proliferator-Activated Receptor γ–Dependent Pathway

Author(s) -

Jana Barlic,

Yuan Zhang,

John F. Foley,

Philip M. Murphy

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.602359

Subject(s) - cx3cr1 , ccr2 , chemokine , microbiology and biotechnology , chemokine receptor , receptor , macrophage , foam cell , peroxisome proliferator activated receptor , biology , medicine , biochemistry , in vitro

Recent genetic data in mouse and humans suggest that the chemokine receptors CCR2 and CX3CR1 are involved in atherogenesis; however, detailed molecular and cellular mechanisms have not been fully delineated.

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