Open AccessInduction of Macrophage Chemotaxis by Aortic Extracts of the mgR Marfan Mouse Model and a GxxPG-Containing Fibrillin-1 Fragment
Author(s) -
Gao Guo,
Patrick Booms,
Marc K. Halushka,
Harry C. Dietz,
Andreas Ney,
Sigmar Stricker,
Jochen Hecht,
Stefan Mundlos,
Peter N. Robinson
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.601674
Subject(s) - fibrillin , medicine , chemotaxis , marfan syndrome , macrophage , fragment (logic) , immunology , microbiology and biotechnology , cardiology , biochemistry , in vitro , biology , receptor , computer science , programming language
The primary cause of early death in untreated Marfan syndrome (MFS) patients is aortic dilatation and dissection.
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