Specific Temporal Profile of Matrix Metalloproteinase Release Occurs in Patients After Myocardial Infarction | Zendy

Carson S. Webb | Zendy; D. Dirk Bonnema | Zendy; S. Hinan Ahmed | Zendy; Amy H. Leonardi | Zendy; Catherine McClure | Zendy; Leslie L. Clark | Zendy; Robert E. Stroud | Zendy; William C. Corn | Zendy; Laura Finklea | Zendy; Michael R. Zile | Zendy; Francis G. Spinale | Zendy

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Specific Temporal Profile of Matrix Metalloproteinase Release Occurs in Patients After Myocardial Infarction

Author(s) -

Carson S. Webb,

D. Dirk Bonnema,

S. Hinan Ahmed,

Amy H. Leonardi,

Catherine McClure,

Leslie L. Clark,

Robert E. Stroud,

William C. Corn,

Laura Finklea,

Michael R. Zile,

Francis G. Spinale

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.600353

Subject(s) - medicine , myocardial infarction , cardiology , matrix metalloproteinase , end diastolic volume , diastole , endocrinology , stroke volume , heart rate , blood pressure

Changes in matrix metalloproteinase (MMP) and tissue inhibitors of MMPs (TIMPs) contribute to left ventricular (LV) remodeling after myocardial infarction (MI). We tested the hypothesis that a specific plasma MMP/TIMP profile would emerge after MI and be associated with the degree of LV dilation.

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