The Chemokine and Chemokine Receptor Profile of Infiltrating Cells in the Wall of Arteries With Cardiac Allograft Vasculopathy Is Indicative of a Memory T–Helper 1 Response
Author(s) -
Jorg van Loosdregt,
Matthijs F.M. van Oosterhout,
Annette H. Bruggink,
D.F. van Wichen,
Joyce van Kuik,
Erica de Koning,
Carla C. Baan,
Nicolaas de Jonge,
F.H.J. Gmelig-Meyling,
Roel A. de Weger
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.597526
Subject(s) - medicine , chemokine , chemokine receptor , cc chemokine receptors , cardiac allograft vasculopathy , ccr2 , pathology , immunology , inflammation , heart transplantation , transplantation
Despite improvement in short-term patient survival after heart transplantation (HTx), long-term survival rates have not improved much, mainly because of cardiac allograft vasculopathy (CAV). Cytokines and chemokines are considered to play an important role in CAV development.
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