Elevated Matrix Metalloproteinase-9 Associated With Stroke or Cardiovascular Death in Patients With Carotid Stenosis
Author(s) -
Nikolaj Eldrup,
Marie-Louise M. Grønholdt,
Henrik Sillesen,
Børge G. Nordestgaard
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.593483
Subject(s) - medicine , stroke (engine) , hazard ratio , stenosis , cardiology , matrix metalloproteinase , cause of death , confidence interval , disease , mechanical engineering , engineering
Matrix metalloproteinase-9 could exhibit an important role in the destabilization of atherosclerotic carotid plaques. We hypothesized that in patients with carotid stenosis, elevated levels of plasma matrix metalloproteinase-9 are associated with ipsilateral stroke or cardiovascular death.
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