Contribution of Clinical Correlates and 13 C-Reactive Protein Gene Polymorphisms to Interindividual Variability in Serum C-Reactive Protein Level
Author(s) -
Sekar Kathiresan,
Martin G. Larson,
Ramachandran S. Vasan,
ChaoYu Guo,
Philimon Gona,
John F. Keaney,
Peter W.F. Wilson,
Christopher NewtonCheh,
Stacy L. Musone,
Amy L. Camargo,
Jared A. Drake,
Daniel Levy,
Christopher J. O’Donnell,
Joel N. Hirschhorn,
Emelia J. Benjamin
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.591271
Subject(s) - single nucleotide polymorphism , snp , genetics , linkage disequilibrium , minor allele frequency , haplotype , c reactive protein , biology , tag snp , genotype , allele , genetic variation , medicine , gene , inflammation
Serum C-reactive protein (CRP) level is a heritable complex trait that predicts incident cardiovascular disease. We investigated the clinical and genetic sources of interindividual variability in serum CRP.
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