Comparative Impact of Multiple Biomarkers and N-Terminal Pro-Brain Natriuretic Peptide in the Context of Conventional Risk Factors for the Prediction of Recurrent Cardiovascular Events in the Heart Outcomes Prevention Evaluation (HOPE) Study | Zendy

Stefan Blankenberg | Zendy; Matthew McQueen | Zendy; Marek Smieja | Zendy; Janice Pogue | Zendy; Cynthia Balion | Zendy; Eva Lonn | Zendy; Hans J. Rupprecht | Zendy; Christoph Bickel | Zendy; Laurence Tiret | Zendy; François Cambien | Zendy; Hertzel C. Gerstein | Zendy; Thomas Münzel | Zendy; Salim Yusuf | Zendy

Open Access

Comparative Impact of Multiple Biomarkers and N-Terminal Pro-Brain Natriuretic Peptide in the Context of Conventional Risk Factors for the Prediction of Recurrent Cardiovascular Events in the Heart Outcomes Prevention Evaluation (HOPE) Study

Author(s) -

Stefan Blankenberg,

Matthew McQueen,

Marek Smieja,

Janice Pogue,

Cynthia Balion,

Eva Lonn,

Hans J. Rupprecht,

Christoph Bickel,

Laurence Tiret,

François Cambien,

Hertzel C. Gerstein,

Thomas Münzel,

Salim Yusuf

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.590927

Subject(s) - medicine , microalbuminuria , hazard ratio , brain natriuretic peptide , context (archaeology) , myocardial infarction , population , proinflammatory cytokine , natriuretic peptide , cardiology , fibrinogen , proportional hazards model , endocrinology , heart failure , inflammation , renal function , confidence interval , environmental health , biology , paleontology

Individual markers of inflammation may add incremental predictive value in the context of conventionally available risk factors. We evaluated the ability of 9 inflammatory biomarkers, microalbuminuria, and N-terminal pro-brain natriuretic peptide (Nt-proBNP) to improve cardiovascular risk prediction beyond that obtained from traditional risk factors in a secondary-prevention population.

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