Important Role of Endogenous Erythropoietin System in Recruitment of Endothelial Progenitor Cells in Hypoxia-Induced Pulmonary Hypertension in Mice | Zendy

Kimio Satoh | Zendy; Yutaka Kagaya | Zendy; Makoto Nakano | Zendy; Yoshitaka Ito | Zendy; Jun Ohta | Zendy; Hiroko Tada | Zendy; Akihiko Karibe | Zendy; Naoko Minegishi | Zendy; Norio Suzuki | Zendy; Masayuki Yamamoto | Zendy; Masao Ono | Zendy; Jun Watanabe | Zendy; Kunio Shirato | Zendy; Naoto Ishii | Zendy; Kazuo Sugamura | Zendy; Hiroaki Shimokawa | Zendy

Open Access

Important Role of Endogenous Erythropoietin System in Recruitment of Endothelial Progenitor Cells in Hypoxia-Induced Pulmonary Hypertension in Mice

Author(s) -

Kimio Satoh,

Yutaka Kagaya,

Makoto Nakano,

Yoshitaka Ito,

Jun Ohta,

Hiroko Tada,

Akihiko Karibe,

Naoko Minegishi,

Norio Suzuki,

Masayuki Yamamoto,

Masao Ono,

Jun Watanabe,

Kunio Shirato,

Naoto Ishii,

Kazuo Sugamura,

Hiroaki Shimokawa

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.583732

Subject(s) - erythropoietin receptor , hypoxia (environmental) , erythropoietin , bone marrow , medicine , haematopoiesis , pulmonary hypertension , progenitor cell , endogeny , right ventricular hypertrophy , endocrinology , immunology , microbiology and biotechnology , biology , stem cell , chemistry , organic chemistry , oxygen

Recent studies have suggested that endogenous erythropoietin (Epo) plays an important role in the mobilization of bone marrow-derived endothelial progenitor cells (EPCs). However, it remains to be elucidated whether the Epo system exerts protective effects on pulmonary hypertension (PH), a fatal disorder encountered in cardiovascular medicine.

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