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Creation of Engineered Cardiac Tissue In Vitro From Mouse Embryonic Stem Cells
Author(s) -
Ximin Guo,
Yunshan Zhao,
Chang Hai-xia,
Changyong Wang,
E Lingling,
XiaoAi Zhang,
Cuimi Duan,
Lingzhi Dong,
Hong Jiang,
Jing Li,
Ying Song,
Xiangzhong Yang
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.583039
Subject(s) - embryoid body , embryonic stem cell , percoll , tissue engineering , microbiology and biotechnology , stem cell , transplantation , matrigel , in vitro , cellular differentiation , somatic cell , medicine , biology , immunology , pathology , adult stem cell , biomedical engineering , biochemistry , gene
Embryonic stem (ES) cells can terminally differentiate into all types of somatic cells and are considered a promising source of seed cells for tissue engineering. However, despite recent progress in in vitro differentiation and in vivo transplantation methodologies of ES cells, to date, no one has succeeded in using ES cells in tissue engineering for generation of somatic tissues in vitro for potential transplantation therapy.

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