Open AccessNoninvasive Targeted Imaging of Matrix Metalloproteinase Activation in a Murine Model of Postinfarction Remodeling
Author(s) -
Haili Su,
Francis G. Spinale,
Lawrence W. Dobrucki,
James Song,
Jing Hua,
Sarah E. Sweterlitsch,
Donald P. Dione,
P Cavaliere,
Conroy Chow,
Brian N. Bourke,
Xiao-yu Hu,
Michael Azure,
Padmaja Yalamanchili,
Richard Liu,
Edward H. Cheesman,
Simon P. Robinson,
David S. Edwards,
Albert J. Sinusas
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.583021
Subject(s) - medicine , matrix metalloproteinase , in vivo , biodistribution , perfusion , nuclear medicine , myocardial infarction , myocardial perfusion imaging , single photon emission computed tomography , biology , microbiology and biotechnology
Time-dependent activation of matrix metalloproteinases (MMPs) after myocardial infarction (MI) contributes to adverse left ventricular (LV) remodeling; however, noninvasive methods to monitor this process serially are needed.
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