Receptor for Advanced-Glycation End Products
Author(s) -
Loredana Bucciarelli,
Michiyo Kaneko,
Radha Ananthakrishnan,
Evis Harja,
Larisse K. Lee,
Yuying C. Hwang,
Shulamit Lerner,
Soliman A. Bakr,
Qing Li,
Yan Lü,
Fei Song,
Wu Qu,
Teodoro Gomez,
Yu Zou,
Shi Fang Yan,
Ann Marie Schmidt,
Ravichandran Ramasamy
Publication year - 2006
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.575993
Subject(s) - rage (emotion) , glycation , medicine , context (archaeology) , nitric oxide , adenosine , nitrotyrosine , ischemia , reperfusion injury , cyclic guanosine monophosphate , receptor , nitric oxide synthase , endocrinology , biology , neuroscience , paleontology
The beneficial effects of reperfusion therapies have been limited by the amount of ischemic damage that occurs before reperfusion. To enable development of interventions to reduce cell injury, our research has focused on understanding mechanisms involved in cardiac cell death after ischemia/reperfusion (I/R) injury. In this context, our laboratory has been investigating the role of the receptor for advanced-glycation end products (RAGE) in myocardial I/R injury.
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