Open AccessRapamycin, but Not FK-506, Increases Endothelial Tissue Factor Expression
Author(s) -
Jan Steffel,
Roberto Adriano Latini,
Alexander Akhmedov,
Dorothee Zimmermann,
Pamela Zimmerling,
Thomas F. Lüscher,
Felix C. Tanner
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.569129
Subject(s) - medicine , tissue factor , microbiology and biotechnology , cancer research , biology , coagulation
Drugs released from stents affect the biology of vascular cells. We examined the effect of rapamycin and FK-506 on tissue factor (TF) expression in human aortic endothelial cells (HAECs) and vascular smooth muscle cells (HAVSMCs).
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