Chronic Atrioventricular Nodal Vagal Stimulation | Zendy

Youhua Zhang | Zendy; Hirotsugu Yamada | Zendy; Steve Bibevski | Zendy; Shaowei Zhuang | Zendy; Kent A. Mowrey | Zendy; Don W. Wallick | Zendy; Seil Oh | Zendy; Todor N. Mazgalev | Zendy

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Chronic Atrioventricular Nodal Vagal Stimulation

Author(s) -

Youhua Zhang,

Hirotsugu Yamada,

Steve Bibevski,

Shaowei Zhuang,

Kent A. Mowrey,

Don W. Wallick,

Seil Oh,

Todor N. Mazgalev

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.568832

Subject(s) - medicine , heart rate , cardiology , atrial fibrillation , anesthesia , stimulation , blood pressure

We have previously demonstrated that selective atrioventricular nodal (AVN) vagal stimulation (AVN-VS) can be used to control ventricular rate during atrial fibrillation (AF) in acute experiments. However, it is not known whether this approach could provide a long-term treatment in conscious animals. Thus, this study reports the first observations on the long-term efficacy and safety of this novel approach to control ventricular rate during AF in chronically instrumented dogs.

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