Selective Activation of Inflammatory Pathways by Intermittent Hypoxia in Obstructive Sleep Apnea Syndrome
Author(s) -
Stephen J. Ryan,
Cormac T. Taylor,
Walter T. McNicholas
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.556746
Subject(s) - medicine , obstructive sleep apnea , hypoxia (environmental) , intermittent hypoxia , sleep apnea , cardiology , chemistry , organic chemistry , oxygen
Obstructive sleep apnea syndrome (OSAS), characterized by intermittent hypoxia/reoxygenation (IHR), is an independent risk factor for cardiovascular disease. We investigated the underlying molecular mechanisms of this association in a translational study.
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