Ghrelin Improves Endothelial Function in Patients With Metabolic Syndrome | Zendy

Manfredi Tesauro | Zendy; Francesca Schinzari | Zendy; Micaela Iantorno | Zendy; Stefano Rizza | Zendy; D Melina | Zendy; Davide Lauro | Zendy; Carmine Cardillo | Zendy

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Ghrelin Improves Endothelial Function in Patients With Metabolic Syndrome

Author(s) -

Manfredi Tesauro,

Francesca Schinzari,

Micaela Iantorno,

Stefano Rizza,

D Melina,

Davide Lauro,

Carmine Cardillo

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.553883

Subject(s) - ghrelin , medicine , endocrinology , sodium nitroprusside , vasodilation , nitric oxide , endothelial dysfunction , acetylcholine , endothelium , metabolic syndrome , saline , hormone , obesity

Metabolic syndrome importantly accelerates the atherosclerotic process, the earliest event of which is endothelial dysfunction. Ghrelin, a gastric peptide with cardiovascular actions, has been shown to inhibit proatherogenic changes in experimental models. This study therefore investigated whether ghrelin administration might beneficially affect endothelial function in metabolic syndrome.

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