Open AccessTargeting Adhesion Molecules as a Potential Mechanism of Action for Intravenous Immunoglobulin
Author(s) -
Varinder Gill,
Christopher J. Doig,
Derrice Knight,
Emma J Love,
Paul Kubes
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.546150
Subject(s) - medicine , intravital microscopy , in vivo , selectin , immunology , integrin , antibody , immune system , cell adhesion molecule , endothelium , in vitro , pharmacology , inflammation , biology , receptor , microcirculation , biochemistry , microbiology and biotechnology
Intravenous immunoglobulin (IVIg) therapy has been shown to have therapeutic benefit in more than 50 inflammatory and immune-related diseases; however, the potential benefit of IVIg in cardiovascular disease is more limited, in part because our understanding of the mechanisms underlying the effects of IVIg in innate immunity is incomplete.
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