CCL2 Polymorphisms Are Associated With Serum Monocyte Chemoattractant Protein-1 Levels and Myocardial Infarction in the Framingham Heart Study
Author(s) -
David H. McDermott,
Qiong Yang,
Sekar Kathiresan,
L. Adrienne Cupples,
Joseph M. Massaro,
John F. Keaney,
Martin G. Larson,
Ramachandran S. Vasan,
Joel N. Hirschhorn,
Christopher J. O’Donnell,
Philip M. Murphy,
Emelia J. Benjamin
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.543579
Subject(s) - medicine , myocardial infarction , framingham heart study , haplotype , linkage disequilibrium , allele , odds ratio , body mass index , cardiology , framingham risk score , genetics , biology , disease , gene
Monocyte chemoattractant protein-1 (MCP-1) is a chemokine strongly implicated in promoting atherosclerosis in animal models, but human genetic evidence is contradictory.
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