Left Ventricular Reverse Remodeling but Not Clinical Improvement Predicts Long-Term Survival After Cardiac Resynchronization Therapy | Zendy

CheukMan Yu | Zendy; Gabe B. Bleeker | Zendy; Jeffrey W.H. Fung | Zendy; Martin J. Schalij | Zendy; Qing Zhang | Zendy; Ernst E. van der Wall | Zendy; Yat-Sun Chan | Zendy; Shun-Ling Kong | Zendy; Jeroen J. Bax | Zendy

Open Access

Left Ventricular Reverse Remodeling but Not Clinical Improvement Predicts Long-Term Survival After Cardiac Resynchronization Therapy

Author(s) -

CheukMan Yu,

Gabe B. Bleeker,

Jeffrey W.H. Fung,

Martin J. Schalij,

Qing Zhang,

Ernst E. van der Wall,

Yat-Sun Chan,

Shun-Ling Kong,

Jeroen J. Bax

Publication year - 2005

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.538272

Subject(s) - medicine , cardiology , heart failure , cardiac resynchronization therapy , ventricular remodeling , receiver operating characteristic , proportional hazards model , survival analysis , log rank test , dilated cardiomyopathy , cardiomyopathy , ejection fraction

In patients with severe heart failure and dilated cardiomyopathy, cardiac resynchronization therapy (CRT) improves left ventricular (LV) systolic function associated with LV reverse remodeling and favorable 1-year survival. However, it is unknown whether LV reverse remodeling translates into a better long-term prognosis and what extent of reverse remodeling is clinically relevant, which were investigated in this study.

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