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Systemic Endothelial Dysfunction in Adults With Cyanotic Congenital Heart Disease
Author(s) -
Erwin Oechslin,
Wolfgang Kiowski,
Ruth Schindler,
Alain Bernheim,
Barbara Julius,
HansPeter BrunnerLa Rocca
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.105.534073
Subject(s) - medicine , vasoconstriction , sodium nitroprusside , brachial artery , cardiology , anesthesia , forearm , vasodilation , endothelial dysfunction , nitric oxide , endocrinology , blood pressure , surgery
Secondary erythrocytosis results in increased shear stress in cyanotic congenital heart disease (CCHD), which may modify the balance between vasodilators and vasoconstrictors and affect systemic endothelial function. Because no data are available on systemic vasomotion, systemic endothelial function and nitric oxide (NO) availability were investigated in CCHD patients.

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