Role of Stromal-Derived Factor-1α in the Induction of Circulating CD34+CXCR4+ Progenitor Cells After Cardiac Surgery | Zendy

Shigetoshi Mieno | Zendy; Basel Ramlawi | Zendy; Munir Boodhwani | Zendy; Richard Clements | Zendy; Keisuke Minamimura | Zendy; Takashi Maki | Zendy; Shuhua Xu | Zendy; Cesario Bianchi | Zendy; Jian Li | Zendy; Frank W. Sellke | Zendy

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Role of Stromal-Derived Factor-1α in the Induction of Circulating CD34+CXCR4+ Progenitor Cells After Cardiac Surgery

Author(s) -

Shigetoshi Mieno,

Basel Ramlawi,

Munir Boodhwani,

Richard Clements,

Keisuke Minamimura,

Takashi Maki,

Shuhua Xu,

Cesario Bianchi,

Jian Li,

Frank W. Sellke

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.001610

Subject(s) - medicine , cardiopulmonary bypass , progenitor cell , cd34 , endothelial progenitor cell , granulocyte colony stimulating factor , anesthesia , stem cell , biology , chemotherapy , genetics

Cardioplegia and cardiopulmonary bypass (CP/CPB) leads to an increase in circulating progenitor cells. The role of stromal-derived factor-1alpha (SDF-1alpha), a key regulator of progenitor cell mobilization, and other cytokines in this process is not clear.

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