Effects of Undersized Mitral Annuloplasty on Regional Transmural Left Ventricular Wall Strains and Wall Thickening Mechanisms | Zendy

Allen C. Cheng | Zendy; Tom C. Nguyen | Zendy; Marcin Malinowski | Zendy; David Liang | Zendy; George T. Daughters | Zendy; Neil B. Ingels | Zendy; D. Craig Miller | Zendy

Open Access

Effects of Undersized Mitral Annuloplasty on Regional Transmural Left Ventricular Wall Strains and Wall Thickening Mechanisms

Author(s) -

Allen C. Cheng,

Tom C. Nguyen,

Marcin Malinowski,

David Liang,

George T. Daughters,

Neil B. Ingels,

D. Craig Miller

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.001529

Subject(s) - medicine , thickening , endocardium , cardiology , mitral regurgitation , anatomy , materials science , polymer science

Undersized mitral annuloplasty, widely used for ischemic and functional mitral regurgitation (MR), has been proposed as an "annular solution to a ventricular problem." Beyond relief of MR, it is thought to improve global left ventricular (LV) shape, hence potentially reducing myocardial stress and promoting beneficial reverse LV remodeling. We previously observed that undersized annuloplasty inhibited systolic wall thickening at the LV base near the mitral annulus. In this study, we measured the effects of undersized annuloplasty on regional transmural LV wall fiber and sheet strains and wall thickening mechanisms.

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