Living Autologous Heart Valves Engineered From Human Prenatally Harvested Progenitors | Zendy

Dörthe Schmidt | Zendy; Anita Mol | Zendy; Christian Breymann | Zendy; Josef Achermann | Zendy; Bernhard Odermatt | Zendy; Matthias Gössi | Zendy; Stefan Neuenschwander | Zendy; René Prêtre | Zendy; Michele Gei | Zendy; Gregor Zünd | Zendy; Simon P. Hoerstrup | Zendy

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Living Autologous Heart Valves Engineered From Human Prenatally Harvested Progenitors

Author(s) -

Dörthe Schmidt,

Anita Mol,

Christian Breymann,

Josef Achermann,

Bernhard Odermatt,

Matthias Gössi,

Stefan Neuenschwander,

René Prêtre,

Michele Gei,

Gregor Zünd,

Simon P. Hoerstrup

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.001040

Subject(s) - progenitor cell , extracellular matrix , tissue engineering , umbilical cord , mesenchymal stem cell , heart valve , chorionic villus sampling , medicine , fetus , andrology , cryopreservation , chorionic villi , heart development , pathology , stem cell , microbiology and biotechnology , anatomy , biomedical engineering , biology , embryonic stem cell , prenatal diagnosis , surgery , embryo , pregnancy , genetics , gene

Heart valve tissue engineering is a promising strategy to overcome the lack of autologous growing replacements, particularly for the repair of congenital malformations. Here, we present a novel concept using human prenatal progenitor cells as new and exclusive cell source to generate autologous implants ready for use at birth.

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