Increased Collagen Deposition and Elevated Expression of Connective Tissue Growth Factor in Human Thoracic Aortic Dissection | Zendy

Xinwen Wang | Zendy; Scott A. LeMaire | Zendy; Li Chen | Zendy; Ying H. Shen | Zendy; Yehua Gan | Zendy; Heather Bartsch | Zendy; Stacey A. Carter | Zendy; Budi Utama | Zendy; Hesheng Ou | Zendy; Joseph S. Coselli | Zendy; Xing Li Wang | Zendy

Open Access

Increased Collagen Deposition and Elevated Expression of Connective Tissue Growth Factor in Human Thoracic Aortic Dissection

Author(s) -

Xinwen Wang,

Scott A. LeMaire,

Li Chen,

Ying H. Shen,

Yehua Gan,

Heather Bartsch,

Stacey A. Carter,

Budi Utama,

Hesheng Ou,

Joseph S. Coselli,

Xing Li Wang

Publication year - 2006

Publication title -

circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 7.795

H-Index - 607

eISSN - 1524-4539

pISSN - 0009-7322

DOI - 10.1161/circulationaha.105.000240

Subject(s) - ctgf , connective tissue , medicine , extracellular matrix , growth factor , type i collagen , fibrosis , masson's trichrome stain , elastin , pathology , endocrinology , biology , microbiology and biotechnology , receptor

Thoracic aortic dissection (TAD) is characterized by dysregulated extracellular matrix. Little is known about the alterations of collagen and stimulators of collagen synthesis, eg, connective tissue growth factor (CTGF), in patients with TAD. In this study, we examined their roles in TAD.

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