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Distal Protection Improved Reperfusion and Reduced Left Ventricular Dysfunction in Patients With Acute Myocardial Infarction Who Had Angioscopically Defined Ruptured Plaque
Author(s) -
Isamu Mizote,
Yasunori Ueda,
Tomohito Ohtani,
Masahiko Shimizu,
Yasuharu Takeda,
Takafumi Oka,
Masahiko Tsujimoto,
Atsushi Hirayama,
Masatsugu Hori,
Kazuhisa Kodama
Publication year - 2005
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.104.532820
Subject(s) - medicine , cardiology , myocardial infarction , culprit , ejection fraction , percutaneous coronary intervention , timi , lesion , coronary arteries , no reflow phenomenon , intravascular ultrasound , artery , surgery , heart failure
Distal protection, in the Saphenous Vein Graft Angioplasty Free of Emboli (SAFER) trial, is demonstrated to prevent distal embolism in the percutaneous coronary intervention of saphenous vein graft. However, in the Enhanced Myocardial Efficacy and Recovery by Aspiration of Liberated Debris (EMERALD) trial, it was not effective in the percutaneous coronary intervention of native coronary arteries in patients with acute myocardial infarction (AMI). We hypothesized that its effectiveness would be determined by lesion characteristics. Therefore, we classified the type of culprit lesion by angioscopy and examined its influence on the effectiveness of distal protection, comparing patients with AMI treated with and without distal protection.

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